Nitric oxide and cardiovascular control

Nitric Oxide Signalling in Vascular Control and Cardiovascular Risk

Molecular control of nitric oxide synthases in the cardiovascular system.

Nitric oxide plays an important role in cardiovascular homeostasis. In this review, the regulation of the three nitric oxide synthase isoforms in the cardiovascular system are examined at molecular and cellular levels. In addition, recent information gleaned from the use of NOS knockout mice are discussed.

Dietary Nitrate, Nitric Oxide, and Cardiovascular Health.

Emerging evidence strongly suggests that dietary nitrate, derived in the diet primarily from vegetables, could contribute to cardiovascular health via effects on nitric oxide (NO) status. NO plays an essential role in cardiovascular health. It is produced via the classical L-arginine-NO-synthase pathway and the recently discovered enterosalivary nitrate-nitrite-NO pathway. The discovery of this...

Nitric oxide, cardiovascular disease and physical exercise.

Mailing Address: Angelina zanesco • Av. 24-A, 1.515 – 13506-900 – Rio Claro,SP Brazil E-mail: [email protected] Manuscript received March 24, 2006; received manuscript revised May 16, 2006; accepted June 1, 2006. Arterial hypertension (AH) has a high incidence in the world’s population and its etiology is multifactorial, involving genetic, environmental and psychological factors1,2. Its prev...

Nitric Oxide Metabolites and Cardiovascular Disease

he chemical reactivity of the free radical gas nitric oxide NO) promotes rapid formation of other nitrogen oxides, ost of which have been considered biologically inert. herefore, the general view has been that NO acts in a aracrine manner, exerting effects only in the close vicinity f its site of production. This view is now rapidly changing ecause it is becoming clear that many of NO’s reactio...